The press release headline was that “topline results demonstrate a dose-dependent and clinically meaningful impact on pain,” and that they showed enough progress to proceed with Phase 2, but to my (completely inexpert) eyes it certainly wasn’t a “wow, this is amazing!” result. They do have plenty of backers, though the big name folks like Thiel and Bezos bought in years ago as venture capital investors, and they certainly are working on interesting-sounding science, so perhaps it will eventually become a big winner. Ample margins.

“Science fiction has become science,” said an anti-aging biotech’s CEO about the company’s completing its $100 million Series B round of financing last week. "While Eylea and Dupixent remain important near-term commercial driver, we think that the oncology business (anchored by Libtayo) will likely drive the next leg of growth for the company in the coming years," write Credit Suisse analysts, who have an Outperform rating (equivalent of Buy) and $700 price target.Regeneron has significantly improved its margins in recent years, so even if the hype behind its REGN-COV2 cocktail fizzles out, long-term growth prospects remain appealing. He starts investing regularly in a corp. and then buying them. The company’s goal is to extend the “health span” of humans, dealing with some diseases and conditions that significantly impact the joy of living like osteoarthritis and macular degeneration, both of which are HUGE markets that are only growing, and this first clinical trial is important in that the drug at least seemed safe and well-tolerated — and perhaps it’s good news on the safety front that they haven’t said anything yet about the Phase 1b and 2 trials that are currently underway. Those first results for their knee osteoarthritis treatment that we saw last year were, at least from my perspective, pretty unimpressive — Phase 1 is mostly designed to make sure a drug is safe enough to try on a broader group of patients, but they also want to see if it is effective… and for many of the indications, the placebo did as well or nearly as well in reducing pain in osteoarthritis sufferers.


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