He was educated at Brighton Grammar School and After four years on the staff at Imperial College, Baldwin moved to the United States: first to One of Baldwin's passions was finding out how nature makes chemicals that researchers cannot. This led him to ‘biomimetic’ synthesis: using the principles of nature to improve the generation of biomolecules in the laboratory.The Baldwin group’s range of interests includes mechanisms of reactions; total synthesis of natural products such as trichoviridin, acromelic acid A, hypoglycin A and lactacystin; and biomimetic synthesis of natural products such as (-)-xestospongin A. Baldwin published over 700 papers. Baldwin was the second son of Frederick C N Baldwin and Olive F Headland.
After four years on the staff at Imperial College, Baldwin moved to the United States: first to Pennsylvania State University in 1967 and then to MIT in 1970 , where he published his most significant work — Baldwin's rules for ring closure reactions. In 1978, he moved to Oxford to become head of the Dyson Perrins Laboratory, where he upgraded its facilities and revolutionised the type of work done, while building links between Organic … It was also where Baldwin met his future wife, Christine Louise Franchi; they married in 1977.
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